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Design of the vaccine study conducted February 2, 2012 to March 1, 2012 during a prolonged outbreak of S. suis disease. All piglets from each weaning cohort were involved in the vaccination study, the pigs to be vaccinated were randomly selected from each litter and vaccinated 1 day before entry into the nursery and again 3 weeks later. All piglets were monitored for mortality during the nursery period.
