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. 2019 Mar 14;14(3):e0213929. doi: 10.1371/journal.pone.0213929

Table 2. Markov Chain Monte Carlo simulations.

Observed Data (Binomial) Prior
(Beta)
Simulation Results
Probabilities Events Total Events No Events Mean Median Credible Interval
GSTP1 High Risk (P1) 45 88 178 114 0.587 0.586 0.538–0.634
Grade 3/4 Nausea (P2) 4 43 33 191 0.139 0.138 0.100–0.181
Second Cycle Administration (P3) 86 88 160 12 0.947 0.948 0.917–0.970
Third Cycle Administration (P4) 64 86 120 40 0.748 0.748 0.692–0.800

Markov chain Monte Carlo simulations performed by Metropolis-Hastings algorithm, describing binomial, beta distributions, as well as the resulting proportions for each simulation and their respective credible intervals.

Notes: MCMC iterations = 12,500; Burn-in = 2,500; MCMC sample size = 10,000