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. 2019 Jan 16;6(3):202–212. doi: 10.1002/mdc3.12720

Table 4.

Correlations of cognitive/UHDRS‐TMS and iSway parameters

MoCA SDMT Stroop Digit span CERAD‐recall Animal naming JLO UHDRS‐TMS
Condition 1: Feet apart, eyes open, firm surface
95% Ellipse sway area (m2/s4) ‐0.258 ‐0.382 ‐0.366 ‐0.073 ‐0.018 ‐0.31 ‐0.32 0.528 *
Total jerk (m2/s5) ‐0.174 ‐0.132 ‐0.293 0.105 0.089 ‐0.15 ‐0.328 0.251
RMS sway (m/s2) ‐0.248 ‐0.208 ‐0.464 0.032 ‐0.001 ‐0.275 ‐0.298 0.321
Feet apart, eyes closed, firm surface
95% Ellipse sway area (m2/s4) ‐0.136 ‐0.064 ‐0.135 0.099 0.089 ‐0.08 ‐0.343 0.189
Total jerk (m2/s5) ‐0.14 0.128 ‐0.133 0.262 0.166 ‐0.086 ‐0.497 * 0.049
RMS sway (m/s2) ‐0.113 0.044 ‐0.281 0.162 0.089 ‐0.086 ‐0.344 0.027
Feet together, eyes open, firm surface
95% Ellipse sway area (m2/s4) ‐0.262 ‐0.439 ‐0.349 ‐0.266 ‐0.075 ‐0.364 ‐0.134 0.679 **
Total jerk (m2/s5) ‐0.224 ‐0.196 ‐0.037 ‐0.006 0.063 ‐0.22 ‐0.209 0.478
RMS sway (m/s2) ‐0.248 ‐0.392 ‐0.319 ‐0.326 ‐0.131 ‐0.456 ‐0.094 0.557*
Feet together, eyes closed, firm surface
95% Ellipse sway area (m2/s4) ‐0.41 ‐0.574 * ‐0.343 ‐0.309 ‐0.142 ‐0.448 ‐.033 0.644 **
Total jerk (m2/s5) ‐0.348 ‐0.468 ‐0.133 ‐0.187 0.033 ‐0.255 ‐0.43 0.525 *
RMS sway (m/s2) ‐0.340 ‐0.554 * ‐0.355 ‐0.318 ‐0.122 ‐0.43 ‐0.308 0.662 **
Feet apart, eyes open, foam surface
95% Ellipse sway area (m2/s4) 0.032 ‐0.314 ‐0.419 ‐0.046 0.121 ‐0.084 ‐0.216 0.479
Total jerk (m2/s5) 0.113 0.039 ‐0.174 0.306 0.280 0.073 ‐0.264 0.062
RMS sway (m/s2) 0.11 ‐0.203 ‐0.468 0.025 0.219 ‐0.066 ‐0.245 0.36
Feet apart, eyes closed, foam surface
95% Ellipse sway area (m2/s4) ‐0.230 ‐0.059 ‐0.038 ‐0.069 ‐0.058 0.081 ‐0.06 0.264
Total jerk (m2/s5) ‐0.108 0.181 ‐0.034 0.248 0.023 0.213 0.009 ‐0.134
RMS sway (m/s2) ‐0.183 ‐0.042 ‐0.116 ‐0.108 0.001 0.07 ‐0.134 0.214
Feet apart, eyes open, dual‐task “C”
95% Ellipse sway area (m2/s4) ‐0.176 ‐0.262 ‐0.302 ‐0.058 0.065 ‐0.304 ‐0.617 ** 0.296
Total jerk (m2/s5) ‐0.14 ‐0.066 ‐0.155 0.062 0.089 ‐0.23 ‐0.549 * 0.133
RMS sway (m/s2) ‐0.126 ‐0.228 ‐0.387 ‐0.064 0.102 ‐0.269 ‐0.581 * 0.23
Feet apart, eyes closed, dual‐task “L”
95% Ellipse sway area (m2/s4) ‐0.143 ‐0.150 ‐0.234 0.111 0.152 ‐0.166 ‐0.569 * 0.186
Total jerk (m2/s5) ‐0.216 ‐0.064 ‐0.138 0.159 0.131 ‐0.118 ‐0.624 ** 0.035
RMS sway (m/s2) ‐0.049 ‐0.076 ‐0.205 0.178 0.253 ‐0.015 ‐0.544 * 0.102
Feet together, eyes open, dual‐task “A”
95% Ellipse sway area (m2/s4) ‐0.142 ‐0.164 ‐0.059 ‐0.028 0.157 ‐0.122 ‐0.527 * 0.292
Total jerk (m2/s5) ‐0.044 ‐0.047 ‐0.202 0.188 0.253 ‐0.15 ‐0.507 * 0.075
RMS sway (m/s2) ‐0.132 ‐0.137 ‐0.038 ‐0.042 0.116 ‐0.139 ‐0.528 * 0.165
Feet together, eyes closed, dual‐task “S”
95% Ellipse sway area (m2/s4) ‐0.245 ‐0.267 ‐0.127 ‐0.112 ‐0.084 ‐0.175 ‐0.557 * 0.395
Total jerk (m2/s5) ‐0.248 ‐0.216 ‐0.149 0.037 0.615 ‐0.114 ‐0.634 ** 0.254
RMS sway (m/s2) ‐0.163 ‐0.275 ‐0.140 ‐0.109 ‐0.045 ‐0.196 ‐0.551 * 0.399

Abbreviations: CERAD, Consortium to Establish a Registry for Alzheimer's disease; CW, Stroop, Color‐Word; JLO, Judgment of Line Orientation; MoCA, Montreal Cognitive Assessment; SDMT, Symbol Digit Modalities Test; TMS, Total Motor Score; UHDRS, Unified Huntington's disease Rating Scale.

Digit span values were correlated with HD patients’ iSWAY performance under varying sensory conditions. Significant differences are bolded. All values are Spearman's rho (r).

*

P < 0.05;

**

P < 0.01;

***

P < 0.001;

***

P < 0.0001.