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. Author manuscript; available in PMC: 2019 Mar 14.
Published in final edited form as: Alzheimers Dement. 2016 Mar;12(3):292–323. doi: 10.1016/j.jalz.2016.02.002

Table 2.

On-going cohorts useful for the study of preclinical AD

Cohort acronym Cohort name Start date End date Ref Website
ADNI Alzheimer’s Disease Neuroimaging Initiative 2004 2009 Weiner et al., 2015 http://www.adni-info.org/Home.aspx
ADNI-GO Alzheimer’s Disease Neuroimaging Initiative Grand
Opportunities
2009 2011 Weiner et al., 2015 http://www.adni-info.org/Home.aspx
ADNI-2 Alzheimer’s Disease Neuroimaging Initiative-2 2011 Ongoing Weiner et al., 2015 http://www.adni-info.org/Home.aspx
AIBL Australian Imaging, Biomarkers and Lifestyle (AIBL)
Flagship Study of Ageing
2006 Ongoing Ellis et al., 2009 http://aibl.csiro.au/
Amsterdam cohort Amsterdam clinical research cohort on dementia 2000 Ongoing van der Flier et al., 2014 NA
BIOCARD Biomarkers of Cognitive Decline Among Normal
Individuals
1995
Restarted
in 2009
2005
ongoing
Soldan et al., 2013 http://www.alzresearch.org/biocard.cfm
HABS Harvard Aging Brain Study 2009 Ongoing Mormino et al., 2014;
Dagley et al., 2015
http://nmr.mgh.harvard.edu/lab/harvardagingbrain
INSIGHT INveStIGation of AlzHeimer’s PredicTors in Subjective
Memory Complainers
2013 Ongoing NA NA
MCSA Mayo Clinic Study of Aging 2004 Ongoing Roberts et al., 2008 & 2012 http://www.mayo.edu/research/centers-programs/
alzheimers-disease-research-center/about
MEMENTO DeterMinants and Evolution of AlzheiMer’s disEase aNd
relaTed disOrders
2011 Ongoing NA http://www.memento-cohort.org/memento
NACC National Alzheimer’s Coordinating Center database 2005 Ongoing Beekly et al., 2004 & 2007 https://www.alz.washington.edu/
Nun Study Nun Study 1986 Ongoing Iacono et al., 2015 https://web.archive.org/web/20131229163933/https://
www.healthstudies.umn.edu/nunstudy/
WU-ADRC Charles and Joanne Knight Alzheimer’s Disease
Research Center at Washington University in Saint
Louis
2004 Ongoing Morris et al., 2009 http://www.adrc.wustl.edu/
UK-ADC University of Kentucky, Alzheimer Disease Center 1985 Ongoing Jicha et al., 2012 http://www.uky.edu/coa/adc
WRAP Wisconsin Registry for Alzheimer’s Prevention 2001 Ongoing La Rue A et al., 2008;
Sager MA., 2005
http://www.wai.wisc.edu/research/wrap.html