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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Carbohydr Res. 2018 Dec 9;472:115–121. doi: 10.1016/j.carres.2018.12.004

Scheme 1.

Scheme 1.

Gram-scale chemoenzymatic synthesis of LeaβProN3 (5). Enzyme abbreviations: SpGalK, Streptococcus pneumoniae galactokinase; BiGalHexNAcP, Bifidobacterium infantis Dgalactosyl-β1–3-N-acetyl-D-hexosamine phosphorylase; BfFKP, Bacteroides fragilis strain NCTC9343 bifunctional L-fucokinase/GDP-fucose pyrophosphorylase; PmPpA, Pasteurella multocida inorganic pyrophosphatase; Hp3/4FT, Helicobacter pylori α1–3/4-fucosyltransferase.