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. Author manuscript; available in PMC: 2020 Mar 13.
Published in final edited form as: Cell Host Microbe. 2019 Feb 19;25(3):367–376.e5. doi: 10.1016/j.chom.2019.01.010

Fig. 3. Characterization of persistent, intermediate and transient antibody clonotypes (see also Table S2).

Fig. 3.

A. Average fraction of persistent, intermediate and transient antibody clonotypes as fraction of the serological repertoire. B-D. IGHV somatic hypermutation mutation (SHM) rates (B), CDR-H3 length (C), and CDR-H3 hydrophobicity (Eisenberg index) (D) are shown where boxes extend from the 25th to 75th percentiles with the whiskers indicating min to max. Statistical significance was determined using the Mann-Whitney U test (** p<0.01; *** p<0.001). E. Frequency of gene usage. F. Relative abundance of CA09+VT04 and CA09-selective antibody clonotypes in the ’14 peak-response sample for each temporal dynamic group. G. Relative abundance of CA09+VT04 and CA09-selective persistent antibody clonotypes. Unknown, binding specificity not determined.