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. 2019 Mar 8;10:429. doi: 10.3389/fimmu.2019.00429

Figure 1.

Figure 1

TLR7 is indispensable for optimal antibody production after RABV immunization. TLR7−/−(n = 12), TLR3−/−(n = 10), or WT mice (n = 11–12) were immunized i.m. with 106 FFU RABV vaccine strain LBNSE in the hind legs. At indicated times post immunization, sera were collected for measuring RABV-specific total IgG (A) and VNA titers (B). Error bars represent standard error of mean (SEM) (*P < 0.05; **P < 0.01; ***P < 0.001).