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. 2019 Mar 8;10:335. doi: 10.3389/fimmu.2019.00335

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Copyright © 2019 Launay, Ndiaye, Conti, Loulergue, Sciré, Landre, Ferruzzi, Nedjaai, Schütte, Auerbach, Marchetti, Saul, Martin and Podda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Individual anti-S. sonnei LPS IgG responses of participants in the boosted group throughout the parent and extension studies. LPS, lipopolysaccharide; IgG, immunoglobulin G; EU, enzyme-linked immunosorbent assay units; D, day. The interval from D225 in the parent study and D1 in the extension study is not represented to scale. Dashed lines represent the limit of detection of the enzyme-linked immunosorbent assay, which varied from plate to plate, from 3·1 to 4·1 EU in the parent study (17) and from 5·5 to 7·4 EU in the extension study.