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. 2019 Mar 8;10:118. doi: 10.3389/fendo.2019.00118

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Copyright © 2019 Chen, Li, Wang, Song, Li, Xie, Li, Chen, Ma, Chen, Lv, Li and Ge.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serum testosterone, LH, and FSH levels after in vivo FGF1 treatment (A) Scheme of the animal experiment of intratesticularly injecting (i.t.) 0, 10, and 100 ng/testis FGF1 on post-EDS day 14 for 14 days; EDS, ethane dimethane sulfonate; LC, Leydig cell; i.p., intraperitoneal injection; (B) Serum testosterone (T) levels; (C) LH levels; (D) FSH levels. Mean ± SEM, n = 6. Asterisk (^*) designates significant difference at P < 0.05 when compared to the control (0 ng/testis FGF1).