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. 2019 Mar 8;10:184. doi: 10.3389/fgene.2019.00184

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Copyright © 2019 Olsvik, Whatmore, Penglase, Skjærven, Anglès d’Auriac and Ellingsen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of early developmental exposure to BPA on zebrafish embryo locomotor activity at 5 dpf. The amount of time (% of total) that 5 dpf zebrafish larvae initiated low (A) or medium (B) levels of activity, and the time medium levels of activity were undertaken (C), under either light (open bars) or dark (black bars) after aqueous exposure to graded levels of BPA (0–30 μM) between 2 and 26 hpf. Letters indicates statistical differences in mean values between treatments (one-way ANOVA, Tukey post hoc test, p < 0.05). Data are the mean ± SEM, n = 3, where each replicate is the average of 8–24 larvae.