Table 4.

Multivariable analysis of DFS, MFS and BCSS in patients treated with adjuvant or no chemotherapy

	n	HRa	95% CI	p Value
Disease-free survival	206
Age at diagnosis		1.02	0.99–1.04	0.128
Tumor grade		0.78	0.40–1.51	0.455
pT		1.07	0.73–1.59	0.723
pN		1.75	1.30–2.34	< 0.001
Metastases-free survival	206
Age at diagnosis		1.01	0.99–1.04	0.275
Tumor grade		1.18	0.47–3.04	0.340
pT		1.70	1.10–2.62	0.017
pN		1.57	1.11–2.21	0.009
Breast cancer-specific survival	203
Age at diagnosis		1.01	0.99–1.04	0.238
Tumor grade		1.46	0.57–3.76	0.427
pT		2.05	1.37–3.10	0.001
pN		1.30	0.91–1.84	0.154
M1 at diagnosis		7.66	2.72–20.08	< 0.001

n number of patients, HR hazard ratio, CI confidence interval, nc not calculable, M1 metastatic disease

^aHR for non-pCR by Cox regression survival analysis using pCR as the baseline value