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. 2019 Mar 14;8(3):22. doi: 10.1038/s41389-019-0132-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a The effect of PCNP on cell migration was measured by wound healing assay; original magnification ×100. b The migration rates of A549 and H1299 cells were calculated. c Soft agar assay was performed to examine the anchorage-independent survival of cells; original magnification ×100. d The number of colonies was calculated. e Transwell assay was performed to assess the migration of A549 and H1299 cells; original magnification ×200. f Transwell assay was performed to assess the invasion of A549 and H1299 cells; original magnification ×200. g The numbers of the migrated cells were calculated. h The numbers of the invasive cells were calculated. Data are presented as mean ± SEM of three independent experiments; **P < 0.01 compared with the Mock group; ^##P < 0.01 compared with the sh-Scb group