Table 3.
Comparison of pre- and post-intervention eGFR-Schwartz stratified according to baseline glomerular hyperfiltration per definition.
| Definition of glomerular hyperfiltration (n, percentile of 144 participants) | Pre eGFR-Schwartz (ml/min) | Post eGFR-Schwartz (ml/min) | Mean of paired differences (pre-post) | 95% confidence interval | P-value |
|---|---|---|---|---|---|
| eGFR-Schwartz > 135 ml/min/1.73 m² (n = 32, 22.2%) | 139.0 ± 32.1 | 128.1 ± 30.5 | 10.8 ± 20.6 | 3.4–18.3 | 0.006* |
| eGFR-Schwartz > 140 ml/min/1.73 m² (n = 22, 15.3%) | 138.1 ± 32.0 | 128.8 ± 33.9 | 9.3 ± 15.4 | 2.5–16.1 | 0.010* |
| eGFR-Schwartz > 150 ml/min/1.73 m² (n = 10, 6.9%) | 154.3 ± 28.4 | 140.9 ± 30.2 | 13.4 ± 14.6 | 3.0–23.8 | 0.017* |
| eGFR-FAS > 135 ml/min/1.73 m² (n = 18, 12.5%) | 142.7 ± 29.2 | 129.3 ± 31.7 | 13.3 ± 15.8 | 5.5–21.2 | 0.002* |
| eGFR-FAS > 140 ml/min/1.73 m² (n = 10, 6.9%) | 153.5 ± 29.4 | 142.6 ± 31.5 | 10.9 ± 19.2 | −2.8–24.6 | 0.105 |
| eGFR-FAS > 150 ml/min/1.73 m² (n = 2, 1.4%) | 141.1 ± 8.9 | 126.9 ± 33.2 | 14.2 ± 24.3 | n/a | n/a |
Abbreviations: eGFR, estimated glomerular filtration rate; n/a, not applicable.