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. 2019 Mar 14;9:4428. doi: 10.1038/s41598-019-40353-8

Table 2.

Results of the pathway enrichment analysis showing significant pathways*.

Analysis Pathway Total metabs in pathway #sig. metabs in pathway Raw p FDR adjusted p
Group Rhythmic Phenylalanine and tyrosine metabolism 13 4 0.000623 0.0492
Linear
Individual Rhythmic Citric acid cycle 23 9 0.000107 0.0085
Urea cycle 20 8 0.000226 0.00892
Linear Citric acid cycle 23 10 2.41E-06 0.00019
Urea cycle 20 8 5.83E-05 0.0023
Malate-aspartate shuttle 8 4 0.00195 0.0337
Beta-alanine metabolism 13 5 0.00207 0.0337
Galactose metabolism 25 7 0.00213 0.0337

*Only metabolic pathways that were significant following FDR correction are shown. The total number of metabolites in the pathway, the number of significant metabolites in the pathway and the raw and FDR adjusted p-values are shown for each pathway. The full results of the pathway enrichment analysis are shown in SI Tables 6–9 and Figs 3–6.