Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 14;9:4599. doi: 10.1038/s41598-018-37622-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effects of KIF4A, 9, 18A, and 23 on survival of LGG patients. The cutoff value determination in Cutoff Finder was based on survival, with significance based on the log-rank test for patient outcome (http://molpath.charite.de/cutoff/assign.jsp). (A) High mRNA expression of KIF4A was significantly associated with poor prognosis (hazard ratio [HR]: 3.4 [95% confidence interval (CI): 2.38–4.86]). In histograms of KIF4A mRNA expression, vertical red lines designate 4.813 as the optimal cutoffs of mRNA derived from the log-rank test. (B) High mRNA expression of KIF18A was significantly associated with: 3.09 [95% CI: 2.17–4.40]). In histograms of KIF18A mRNA expression, vertical red lines designate 3.346 as the optimal cutoffs of mRNA derived from the log-rank test. (C) High mRNA expression of KIF23 was significantly associated with poor prognosis (HR: 3.62 [95% CI: 2.52–5.21]). In histograms of KIF23 mRNA expression, vertical red lines designate 4.322 as the optimal cutoffs of mRNA derived from the log-rank test. (D) High mRNA expression of KIF9 was significantly associated with poor prognosis (HR: 2.17 [95% CI: 1.39–3.41]). In histograms of KIF9 mRNA expression, vertical red lines designate 4.835 as the optimal cutoffs of mRNA derived from the log-rank test.