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. 2019 Mar 14;9:4467. doi: 10.1038/s41598-019-40811-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The DEGs of overexpressed GATA3 in the volcano plot and heatmap. (A) Heatmap of vector and GATA3 overexpression samples based on the identified 100 robust differentially expressed (50 top upregulated and 50 top downregulated) genes. The highest expression values of DEGs are displayed in pink, and the lower expression values gradually fade toward white color. the lowest expression values of DEGs are shown in blue, with higher values gradually fading toward white color. (B) The volcano plot shows the DEG distributions in both up- and downregulated genes. The green color shows the downregulated genes, while the red indicates the upregulated genes.