Table 2.
Diseases associated with Lyme, by ICD-9 code. A total of 3,639 diseases were tested.
| Time (year) | Direction | Disease (CCS) | ICD9 | Disease (ICD9) | Lyme First | Disease First | Same Time | p value (binomial) | Prob. (binomial) | p value (logistic regression) | OR (logistic regression) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | — | HIV infection | V08 | HIV positive NOS | 0 | 21 | 8 | 1.21E-02 | 0.72 | 1.80E-05 | 2.17 |
| 5 | — | Administrative/social admission | V20.2 | Routin child health exam | 16 | 49 | 4 | 3.18E-04 | 0.71 | 1.31E-02 | 2.08 |
| 5 | + | Nutritional deficiencies | 268.9 | Vitamin D deficiency NOS | 203 | 124 | 36 | 1.37E-02 | 0.56 | 1.20E-177 | 5.64 |
| 5 | + | Cataract | 366.9 | Cataract NOS | 40 | 18 | 7 | 4.08E-02 | 0.62 | 2.90E-30 | 4.27 |
| 5 | + | Acute bronchitis | 466.0 | Acute bronchitis | 36 | 16 | 3 | 1.50E-02 | 0.65 | 4.02E-21 | 3.56 |
| 5 | + | Nonmalignant breast conditions | 793.80 | Unspecified abnormal mammogram | 28 | 12 | 0 | 8.29E-03 | 0.70 | 8.92E-10 | 2.61 |
| 10 | — | HIV infection | V08 | HIV positive NOS | 0 | 24 | 8 | 3.50E-03 | 0.75 | 1.80E-05 | 2.17 |
| 10 | — | Disorders of lipid metabolism | 272.0 | Pure hypercholesterolem | 84 | 159 | 50 | 8.04E-02 | 0.54 | 1.60E-30 | 2.22 |
| 10 | — | Disorders of lipid metabolism | 272.4 | Hyperlipidemia NEC/NOS | 97 | 187 | 64 | 9.01E-02 | 0.54 | 1.06E-18 | 1.78 |
| 10 | — | Essential hypertension | 401.9 | Hypertension NOS | 96 | 247 | 120 | 8.16E-02 | 0.53 | 9.83E-08 | 1.39 |
| 10 | — | Administrative/social admission | V20.2 | Routin child health exam | 17 | 54 | 4 | 8.82E-05 | 0.72 | 1.31E-02 | 2.08 |
| 10 | + | Nutritional deficiencies | 268.9 | Vitamin D deficiency NOS | 211 | 124 | 36 | 4.67E-03 | 0.57 | 1.20E-177 | 5.64 |
| 10 | + | Cataract | 366.16 | Senile nuclear cataract | 17 | 2 | 1 | 1.29E-03 | 0.85 | 2.94E-03 | 1.97 |
| 10 | + | Cataract | 366.9 | Cataract NOS | 45 | 21 | 7 | 3.02E-02 | 0.62 | 2.90E-30 | 4.27 |
| 10 | + | Inflammation; infection of eye (except that caused by tuberculosis or sexually transmitted disease) | 373.00 | Blepharitis NOS | 33 | 2 | 1 | 1.14E-07 | 0.92 | 2.27E-14 | 3.79 |
| 10 | + | Other eye disorders | 375.15 | Tear film insuffic NOS | 24 | 11 | 1 | 3.26E-02 | 0.67 | 4.44E-12 | 3.36 |
| 10 | + | Acute bronchitis | 466.0 | Acute bronchitis | 37 | 17 | 3 | 1.66E-02 | 0.65 | 4.02E-21 | 3.56 |
| 10 | + | Nonmalignant breast conditions | 793.80 | Unspecified abnormal mammogram | 31 | 12 | 0 | 2.70E-03 | 0.72 | 8.92E-10 | 2.61 |
This table includes only the ICD-9 diseases that are classified into the CCS-single-level categories shown in (a), and a full list of associations is provided in Supplementary Table 1.