Table 2.
Basic information of candidate SNPs and minor allele frequency between cases and controls
| SNP rs# | Chromosome | Position | Role | Alleles A/B | Gene(s) | MAF | p ‐HWE | OR | 95%CI | p a | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | ||||||||||
| rs3017895 | 4 | 89649491 | 3′‐UTR | A/T | FAM13A | 0.322 | 0.266 | 0.435 | 1.32 | 1.03–1.68 | 0.028 * |
| rs1059122 | 4 | 89647424 | 3′‐UTR | G/A | FAM13A | 0.523 | 0.473 | 0.179 | 1.22 | 0.97–1.53 | 0.081 |
Alleles A/B: Minor/major alleles; CI: confidence interval; HWE: Hardy–Weinberg equilibrium; MAF, minor allele frequency; OR: odds ratio; SNP: single‐nucleotide polymorphism.
Bold highlights the value of p and OR (95%CI) with statistical significance.
a
p values were calculated using two‐sided chi‐squared test (the major allele of each SNP was a reference allele).
*
p ≤ 0.05 indicates statistical significance.