Table 2.

Allele frequencies in cases and controls and odds ratio estimates for ONFH risk

SNP	Gene(s)	Band	Alleles A/B	MAF		p‐HWE	OR (95% CI)	p‐value
				Case	Control
rs11674595	IL1R2	2q11.2	C/T	0.267	0.211	0.250	1.37 (1.07–1.75)	0.012 a
rs4851527	IL1R2	2q11.2	A/G	0.259	0.289	0.486	0.86 (0.68–1.09)	0.214
rs719250	IL1R2	2q11.2	T/G	0.333	0.317	0.912	1.07 (0.86–1.35)	0.533
rs3218896	IL1R2	2q11.2	C/T	0.173	0.150	0.351	1.18 (0.89–1.57)	0.252
rs3218977	IL1R2	2q11.2	G/A	0.263	0.251	1.000	1.07 (0.84–1.36)	0.592
rs2072472	IL1R2	2q11.2	G/A	0.208	0.200	0.766	1.05 (0.81–1.37)	0.696
rs10490571	IL1R1	2q12.1	T/C	0.215	0.168	0.061	1.35 (1.04–1.77)	0.025 a
rs12712127	IL1R1	2q12.1	G/A	0.290	0.215	0.000	1.50 (1.17–1.91)	0.001
rs956730	IL1R1	2q12.1	A/G	0.248	0.250	0.016	0.99 (0.78–1.26)	0.940
rs3917225	IL1R1	2q12.1	T/C	0.419	0.348	0.074	1.35 (1.09–1.68)	0.006 a
rs3917318	IL1R1	2q12.1	G/A	0.498	0.497	0.045	1.01 (0.82–1.24)	0.951

SNP: single‐nucleotide polymorphism; MAF: minor allele frequency; HWE: Hardy–Weinberg equilibrium; OR: odds ratio; CI: confidence interval.

^aIn bold, p < 0.05 indicates statistical significance

In bold, p‐HWE < 0.05 be excluded.