Figure 6.

Model for nobiletin inhibiting proliferation and inducing apoptosis. Nobiletin inhibits PARP‐2 level, which activates SIRT1, regulates the downstream AMPK‐mTOR signaling, and suppresses the growth of C666‐1 cell

Model for nobiletin inhibiting proliferation and inducing apoptosis. Nobiletin inhibits PARP‐2 level, which activates SIRT1, regulates the downstream AMPK‐mTOR signaling, and suppresses the growth of C666‐1 cell