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. 2019 Jan 14;38(6):e98791. doi: 10.15252/embj.201798791

Figure EV4. Performance and DTs at different discrimination tasks.

Figure EV4

  1. Experimental design used to test effects on olfaction. Tam, tamoxifen; Dox, doxycycline.
  2. Line graphs indicating the proportion of correct responses (performance) for bins of 100 trials during testing with (from left to right): pure and binary mixture of AA vs. EB and pure and 1:10 diluted binary mixture of (−) vs. (+)‐octanols. Discontinuous line indicates the similar 95% plateau performance of 4D (black) and 4D+ (red) mice.
  3. Box and whiskers plots representing the DTs calculated at 95% performance. Note that DTs are slower using the automated olfactometer compared with the previously used olfactometers owing to differences in odor port design (Abraham et al, 2010). (C) AA, amyl acetate; EB, ethyl butyrate; oct, octanol.
Data information: Mean ± SEM with significance tested by repeated measures two‐way ANOVA (B) or unpaired Student's t‐test with outliers identified by Tukey's test (C). Cohorts of N = 21/17 or 15/10 for 1:10 dilution (B; right) 4D/4D+ mice were used.