Table 3.
Illustrative examples of block copolypeptides reported in the literature.
| Type of Block Copolymer | Block Copolypeptide | Reference |
|---|---|---|
| Diblock | poly[γ-benzyl-l-glutamate-b-(l-glutamic Acid)] | [121] |
| Diblock | Nε-4-phenylbenzamido-l-lysine-b-Nε-trifluoroacetyl-l-lysine | [120] |
| Diblock | o-(tetra-o-acetyl-d-glucopyranosyl)-l-serine-NCA-b-alanine NCA | [119] |
| Diblock | poly(γ-benzyl-l-glutamate)-b-polyglycine | [122] |
| Diblock | poly[γ-benzyl-l-glutamate-b-(poly(Nε-carbobenzoxy-l-lysine)], poly[γ-benzyl-l-glutamate-b-polyglycine], poly[γ-benzyl-l-glutamate-b-poly(l-tyrosine)], poly[γ-benzyl-l-glutamate-b-poly(poly(l-leucine)]. | [76] |
| Diblock | poly(γ-benzyl-l-glutamate)-b-poly(l-lysine) | [123] |
| Diblock | poly[γ-benzyl-l-glutamate-b-(poly(Nε-carbobenzoxy-l-lysine)], and block copolypeptides containing l-leucine and l-proline) | [130] |
| Diblock | poly(Nε-2[2-(2-methoxyethoxy)ethoxy]acetyl-l-lysine)-b-poly(l-aspartic acid, sodium salt) | [131] |
| Diblock | poly(l-lysine Hbr) or poly(l-glutamic acid sodium salt), and helical, hydrophobic segments of poly(l-leucine) | [132,133] |
| Diblock | diblock copolypeptides of hydrophilic l-lysine or l-glutamic acid and hydrophobic leucine or valine | [134] |
| Diblock | poly(l-lysine)-b-poly(l-glycine), poly(l-lysine)-b-poly(l-alanine), poly(l-lysine)-b-poly(l-phenylalanine) | [135] |
| Diblock | poly(S-(o-nitrobenzyl)-l-cysteine)-b-poly(ethylene glycol) (PNBC-b-PEO) block copolymers | [50] |
| Diblock | Hydrophilic (glutamic acid or lysine) and one nonpolar block (alanine) or with both hydrophilic blocks with opposite charges (glutamic acid and lysine) | [136] |
| Diblock | Poly(l-lysine)-b-poly(l-glycine) | [137,138] |
| Diblock | poly(l-lysine)-b-poly(l-phenylalanine) | [139] |
| Diblock | poly(l-methionine)65-b-poly(l-leucine0.5-stat-l-phenylalanine0.5)20 | [140] |
| Diblock/Triblock | poly-l-lysine-b-poly-l-leucine and poly-l-lysine-b-poly-l-leucine-b-poly-l-lysine | [128] |
| Triblock | poly[(γ-benzyl-l-glutamate)-b-(l-leucine)-b-(γ-benzyl-l-glutamate)] and the corresponding poly[(l-Glutamic Acid)-b-(l-leucine)-b-(l-Glutamic Acid)], poly(Nε-carbobenzoxy-l-lysine)-b-(γ-benzyl-l-glutamate)-b-(poly-Nε-carbobenzoxy-l-lysine) | [76,126,127,141] |
| Triblock | poly(l-homoarginine HCl)m-block-poly(Lglutamate Na)n-block-poly(l-leucine)20 | [6] |
| Triblock | poly[(Nε-carbobenzoxy-l-lysine)-b-poly(l-leucine)-b-poly(Nε-carbobenzoxy l-lysine)] | [128,129] |
| Tetrablock | Poly(γ-benzyl-l-glutamate)-b-poly(l-alanine)-b-poly(Nε-benzyloxycarbonyl-l-lysine)-b-poly(β-benzyl-l-aspartate) | [79] |