Table 5.
Characterization of PEG-b-PCL (2000–12,000) nanoparticles made by nanoprecipitation with lipid POPG (POPG NPs). (Mean ± SD) (n = 3).
| Polymer | pH of Water Phase | Mean Diameter by Number (nm) | Mean Diameter by Intensity (nm) | Mean PDI | Mean Zeta Potential (mV) | Mean E.E. (%) | |
|---|---|---|---|---|---|---|---|
| mPEG-b-PCL | 3 | 63.6 ± 17.2 | 245.2 ± 12.4 | 0.34 ± 0.01 | −52.1 ± 2.9 | P3V8 | 100.00 ± 0.00 |
| QBP1 | 98.06 ± 2.37 | ||||||
| 5 | 57.6 ± 20.5 | 269.9 ± 21.5 | 0.34 ± 0.02 | −44.1 ± 4.6 | P3V8 | 94.85 ± 0.41 | |
| QBP1 | 96.07 ± 0.26 | ||||||
| 7 | 87.3 ± 26.5 | 319.0 ± 60.8 | 0.33 ± 0.03 | −44.8 ± 7.9 | P3V8 | 94.33 ± 0.11 | |
| QBP1 | 88.48 ± 1.97 | ||||||
| Mix ligands PEG-b-PCL | 3 | 80.8 ± 16.5 | 246.2 ± 14.2 | 0.31 ± 0.01 | −38.7 ± 0.8 | P3V8 | 100.00 ± 0.00 |
| QBP1 | 99.36 ± 0.56 | ||||||
| 5 | 74.9 ± 37.3 | 284.1 ± 40.3 | 0.31 ± 0.03 | −47.6 ± 4.4 | P3V8 | 98.27 ± 0.33 | |
| QBP1 | 100.00 ± 0.00 | ||||||
| 7 | 63.5 ± 1.9 | 321.0 ± 107.3 | 0.32 ± 0.05 | −42.0 ± 2.4 | P3V8 | 94.68 ± 0.69 | |
| QBP1 | 84.89 ± 5.57 | ||||||