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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Ann Surg. 2018 Oct;268(4):632–639. doi: 10.1097/SLA.0000000000002955

Table 4:

Proportional hazards model for post-recurrence survival based on time since most recent previous surveillance.

HR (95% CI) p-value
Time since last surveillance (per month) 1.02 (0.99, 1.04) 0.432
 ≥ 14 months since last surveillance 1.01 (0.62, 1.65)
Recurrence: Distant (reference) 0.020
 Local 0.78 (0.64, 0.96)
Detection: Asymptomatic < 0.001
 Symptomatic 1.49 (1.20, 1.85)
Age (per decade) 1.17 (1.08, 1.27) < 0.001
Sex: Male 0.001
 Female 0.76 (0.64, 0.89)
Histology: Adenocarcinoma 0.023
 Squamous 1.29 (1.05, 1.60)
 Other histology 1.20 (0.96, 1.49)
Surgery: Lobectomy 0.837
 Pneumonectomy 0.85 (0.58, 1.23)
 Segmentectomy 1.01 (0.66, 1.55)
 Wedge resection 1.04 (0.80, 1.35)
Chronic obstructive pulmonary disease 1.04 (0.85, 1.28) 0.684
Congestive heart failure 1.47 (1.13, 1.92) 0.004
Coronary artery disease 0.80 (0.64, 0.98) 0.034
Diabetes 1.17 (0.91, 1.51) 0.229
Peripheral vascular disease 1.49 (1.16, 1.91) 0.002
Psychiatric 0.99 (0.74, 1.33) 0.963
Substance abuse 1.36 (0.96, 1.94) 0.083