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. 2019 Feb 20;11(2):379. doi: 10.3390/polym11020379

Table A2.

DTA data of AMX, excipients, and their binary mixtures at 1:1, 1:2, and 2:1 proportions (AMX: excipient).

Sample Event Start–End (°C) Peak (°C) ΔH (J·g−1)
AMX First 66.41–126.28 98.67 −283.69
ASP First 59.72–91.16 80.23 −35.43
Second 178.70–196.78 188.87 −229.97
Third 243.79–255.77 249.17 −183.82
Fourth 303.23–347.95 325.47 −281.75
AMX + ASP (1:1) First 55.18–121.32 89.03 −148.52
Second 170.02–193.65 183.90 −123.74
Third 222.86–244.21 235.55 −64.54
Fourth 309.01–337.42 322.89 −14.97
AMX + ASP (1:2) First 53.71–118.83 98.93 −138.94
Second 175.18–193.76 184.97 −164.40
Third 226.99–244.48 237.58 −87.29
Fourth 283.28–304.42 283.53 −6.79
Fifth 308.47–332.22 329.86 −13.74
AMX + ASP (2:1) First 50.39–130.82 98.62 −193.24
Second 169.74–193.95 184.25 −85.90
Third 217.74–241.31 234.78 −25.09
CBP First 56.25–113.69 86.63 −185.54
Second 181.79–246.38 213.91 −182.44
Third 255.62–293.73 272.20 −95.02
Fourth 351.44–368.78 362.72 14.49
AMX + CBP (1:1) First 83.02–122.89 104.39 −70.91
Second 303.89–383.38 336.16 −100.08
AMX + CBP (1:2) First 56.25–113.69 86.63 −185.54
Second 181.79–246.38 213.91 −182.44
Third 255.62–293.73 272.20 −95.02
Fourth 351.44–368.78 362.72 14.49
AMX + CBP (2:1) First 58.93–134.65 106.95 −195.85
CMC First 71.60–126.66 97.97 −397.78
Second 286.00–301.70 290.81 133.76
Third 312.77–319.61 317.74 7.90
AMX + CMC (1:1) First 83.19–128.16 100.75 −177.71
Second 277.55–318.74 295.42 198.44
AMX + CMC (1:2) First 75.51–119.36 92.61 −152.56
Second 275.67–316.37 295.63 179.56
AMX + CMC (2:1) First 52.53–128.94 91.95 −239.41
Second 278.07–320.79 297.34 114.52
CSD First 27.62–48.97 35.59 21.10
AMX + CSD (1:1) First 80.02–107.25 105.60 −9.19
AMX + CSD (1:2) First 55.12–124.84 97.85 −129.91
AMX + CSD (2:1) First 54.21–134.64 100.47 −181.98
FRU First 87.79–121.41 107.92 −47.51
Second 190.63–210.33 210.13 28.19
Third 254.48–307.24 279.24 309.91
AMX + FRU (1:1) First 118.69–134.69 126.09 −76.91
Second 191.94–203.81 195.05 6.15
Third 220.61–235.04 222.28 13.5
AMX + FRU (1:2) First 90.91–108.74 101.92 −12.26
Second 141.26–164.2 149.76 30.95
Third 218.17–248.33 237.24 136.48
AMX + FRU (2:1) First 115.32–138.45 121.37 −294.63
HEC First 59.73–101.83 77.73 −113.76
Second 325.83–355.15 343.28 237.51
Third 359.21–368.49 364.60 10.15
AMX + HEC (1:1) First 56.25–128.83 98.58 −313.54
Second 320.82–353.96 344.65 26.04
AMX + HEC (1:2) First 59.67–134.47 104.51 −345.83
Second 322.98–369.57 346.98 181.95
AMX + HEC (2:1) First 45.45–119.58 91.22 −281.17
Second 376.04–396.15 383.22 17.62
HPMC First 61.68–112.83 91.18 −138.66
Second 337.66–373.63 356.09 −89.52
AMX + HPMC (1:1) First 64.97–117.03 93.44 −11.91
Second 285.24–334.35 316.21 −46.32
AMX + HPMC (1:2) First 61.99–112.82 89.43 −103.01
Second 336.40–349.92 341.99 −14.46
Third 382.45–428.34 374.75 −12.19
AMX + HPMC (2:1) First 92.12–125.29 101.68 −86.69
Second 338.29–368.38 344.15 9.27
LAC First 142.89–156.77 146.52 −183.12
Second 214.47–226.32 219.34 −226.34
Third 237.71–246.58 241.72 −3.62
Fourth 284.67–323.80 304.85 −137.36
AMX + LAC (1:1) First 84.56–110.61 99.90 −2.19
Second 141.61–156.27 147.46 −25.28
Third 199.51–211.00 207.32 −45.78
AMX + LAC (1:2) First 142.76–157.07 146.90 −216.02
Second 204.29–216.80 211.31 −463.07
AMX + LAC (2:1) First 82.80–126.49 97.99 −15.28
Second 139.37–155.15 147.19 −59.60
Third 202.50–218.73 210.83 −72.55
MAN First 165.99–177.62 169.89 −450.53
Second 280.49–353.91 321.83 −812.74
AMX + MAN (1:1) First 157.97–171.08 163.10 −50.80
AMX + MAN (1:2) First 157.32–175.31 165.63 −503.47
Second 237.23–329.28 304.15 −585.71
AMX + MAN (2:1) First 85.87–125.00 112.56 −22.99
Second 154.30–171.26 162.94 −130.24
Third 283.03–340.83 325.73 −47.41
MST First 45.31–54.35 50.91 −7.99
Second 119.80–137.59 129.00 −255.25
Third 154.00–159.72 156.07 −4.08
Fourth 276.41–343.01 319.75 −379.49
AMX + MST (1:1) First 123.76–138.22 127.43 −71.44
AMX + MST (1:2) First 112.93–134.13 123.68 −126.77
Second 341.03–401.02 366.74 −204.32
AMX + MST (2:1) First 120.27–135.90 126.36 −51.45
PVP K-30 First 53.58–125.06 97.61 −515.18
AMX + PVP (1:1) First 54.43–116.18 87.01 −147.70
AMX + PVP (1:2) First 89.84–141.02 116.75 −202.44
AMX + PVP (2:1) First 51.22–126.61 92.02 −273.58
SAC First 42.16–67.71 60.76 −139.27
Second 114.9–136.39 120.25 −281.00
Third 126.89–131.67 129.85 −5.52
Fourth 361.66–370.92 365.15 −210.17
AMX + SAC (1:1) First 42.16–67.71 60.76 −139.27
Second 114.9–136.39 120.25 −281.00
Third 361.66–370.92 365.15 −26.91
AMX + SAC (1:2) First 64.6–74.86 70.58 −10.73
Second 115.34–135.1 126.04 −40.79
Third 140.88–152.57 145.45 −55.66
Fourth 349.31–364.54 357.99 −65.39
AMX + SAC (2:1) First 66.61–83.47 73.97 −29.27
Second 128.34–147.75 137.68 −26.45
Third 348.6–365.37 356.49 −18.02
TAL First 38.13–51.22 44.70 −11.76
AMX + TAL (1:1) First 74.88–111.55 99.76 −27.33
AMX + TAL (1:2) - - - -
AMX + TAL (2:1) First 65.31–129.85 106.16 −113.68