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Mitochondrial membrane depolarization by PAMAM-FHR/pJDK-apoptin. (A) GBL-14 and (B) dermal fibroblasts were incubated with polymer/pJDK or pJDK-apoptin complexes. The cells were analyzed for MMP after TMRE staining and then evaluated by flow cytometry. FCCP was used as a positive control. Results are shown as the mean ± standard deviation, n = 3. MMP, mitochondrial membrane potential, FCCP, cyanide 4-(trifluoromethoxy)-phenylhydrazone.
