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. 2019 Feb 12;14(3):394–402. doi: 10.2215/CJN.05240418

Figure 1.

Figure 1.

Schematic of the displacer concept. A displacer substance is infused into the arterial (prefilter) bloodline, where the displacer molecule competes with protein-bound toxins for binding sites. This competition results in higher free toxin levels, facilitating higher toxin removal rates. The use of multiple displacer molecules (“displacer cocktail”) is possible and has been tested ex vivo (19).