Table 2.
Comparison of baseline mean for BMI and serum irisin, glucose indices, and lipids in overweight or obese patients with non-alcoholic fatty liver disease (NAFLD)
| Baseline Dependent Variables | Cardamom (n = 43) n(%) or Mean (SD) |
Placebo (n = 44) n(%) or Mean (SD) |
P-value | |
|---|---|---|---|---|
| BMI (kg/m2) | 25–29.99 | 16 (37.2) | 17 (38.6) | 0.8b |
| 30–34.99 | 27 (62.8) | 27 (61.4) | ||
| FBS (mg/dl) | 93.3 (7.6) | 91.5 (7.9) | 0.3c | |
| FBI (μIU/ml) | 8.1 (0.6) | 7.9 (0.9) | 0.7c | |
| HOMA-IR (score) | 1.8 (0.1) | 1.7 (0.2) | 0.1a | |
| QUICKI (score) | 0.34 (0.005) | 0.35 (0.008) | 0.1c | |
| Irisin (ng/ml) | 25.3 (2.9) | 25.2 (2.2) | 1.0c | |
| TC (mg/dl) | 204.5 (25.0) | 205.0 (26.7) | 0.9a | |
| TG (mg/dl) | 170.2 (77.4) | 178.0 (74.7) | 0.6a | |
| LDL-c (mg/dl) | 125.1 (26.3) | 124.4 (21.7) | 0.8a | |
| HDL-c (mg/dl) | 44.7 (9.7) | 45.3 (8.7) | 0.7a | |
at-test; bChi-square; cMann-Whitney; BMI body mass index, HOMA-IR homeostasis model assessment-insulin resistance, QUICKI quantitative insulin sensitivity check index, FBS fasting blood sugar, FBI fasting blood insulin, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein-cholesterol