Fig. 2.

Levels of ROS and oxidized PRXs in mouse islet cells treated with glucose. a and b Oxidized PRXs were increased in a glucose concentration-dependent manner, and the signal for PRX3-SO3H was dramatically enhanced at 2 h of 16.7mM as compared to 5 .6mM glucose stimulation. c ROS production in mouse islet cells stimulated with 16.7mM glucose was significantly elevated at 1 h, 2 h, and 3 h respectively (*1 h: F = 4.641, P < 0.001; 2 h: F = 4.353, P < 0.001; 3 h: F = 3.460, P < 0.001). There was no significant difference in ROS production between 5 .6mM glucose stimulation and non-treated cells