Table 2.
Parameter | Coefficient | 95% confidence interval | P value |
---|---|---|---|
Day 7 Day 0 decline in haemoglobin concentration | |||
D0 haemoglobin concentration | −0.34 | −0.45– −0.24 | < 0.001 |
D0 parasite count | −2.69 × 10−7 | −4.81 × 10−6 – −5.60 × 10− 7 | 0.014 |
On DHAPP+ SLDPQ | 0.48 | 0.08–0.88 | 0.019 |
Haemoglobin dynamics over 28 days | |||
DHAPP+SLDPQ | 0.69 | 0.11 ─ 1.27 | 0.019 |
Age | 0.034 | 0.014–0.055 | 0.001 |
Male | 0.91 | 0.19–1.62 | 0.013 |
Reticulocyte dynamics | −0.12 | − 0.17 – − 0.06 | 0.000 |
Total malaria attributable fall in haemoglobin | |||
Treatment failure | −1.28 | −2.27 – −0.029 | 0.012 |
D7 haemoglobin concentration | −0.53 | −0.74 – − 0.32 | < 0.001 |
Male | 0.99 | 0.004–1.99 | 0.049 |
Haemoglobin recoverya | |||
Male | 7.2 | 1.3–40.0 | 0.025 |
Age | 1.04 | 1.001–1.08 | 0.045 |
D0 haemoglobin concentration | 0.51 | 0.34–0.76 | 0.001 |
Reticulocyte dynamics | |||
D0 haemoglobin concentration | −0.320 | − 0.420 ─ -0.219 | < 0.001 |
aBy logistic regression, the odds ratio is reported with 95% confidence interval