Table 1.
Summary of the included articles
| Author | Year | Country | Design | Study period | Year CQ PC | Years CQ not in use | CQ still used | Prev. of Pfcrt K76T after CQ policy change | Prev. of Pfmdr1 N86Y after CQ policy change |
|---|---|---|---|---|---|---|---|---|---|
| Andriantsoanirina [37] | 2010 | Madagascar | RCT | 2006–2007 | 2005 | 01 | Yes | 0.32% (2/621) | 44.5% (147/330) |
| Achieng [19] | 2015 | Kenya | CSS | 1995–2014 | BF/AF | NA | Yes | 28.5% (212/745) | 14.9% (111/745) |
| Asih [45] | 2009 | Indonesia | CSS | 2007 | 2004 | 3 | NR | 89.2% (345/387) | 42.3% (82/194) |
| Atroosh [36] | 2012 | Malaysia | CSS | 2007–2011 | NR | NA | Yes | 52.7% (39/75) | 5.3% (4/75) |
| Baraka [15] | 2015 | Burkina Faso | RCT | NR | 2005 | NA | NR | 48.7% (130/272) | 61.8% (168/267) |
| Baraka [76] | 2018 | DRC/Uganda | RCT | 2012–2014 | NR | NR | NR | NR | DRC: 37.9% (278/732) Uganda: 7.5% (55/732) |
| Bo Huang [35] | 2016 | Grande Comore Island | CSS | 2006–2014 | 2004 | 2 | Yes | 49.5% (100/202) | 66.8% (135/202) |
| Sutar [41] | 2013 | India | CSS | 2008 | 1982 | 26 | No | 77.6% (156/201) | 59.5% (119/200) |
| Das [28] | 2017 | India | CT | 2008–2013 | 1982 | 26 | Yes | Kolkata: 69.1% (540/781) Purulia: 50.97% (398/781) |
Kolkata: 44.3% (346/781) Purulia: 65.6% (512/781) |
| Frank [29] | 2011 | Gabon | CSS | 1995–2007 | 2003 | 8 | Yes | 99.2% (356/359) | NR |
| Gadalla [77] | 2015 | Tanzania | Cohort | 2003–2006 | 2001 | 2 | NR | 93.6% (219/234) | 91.6% (163/234) |
| Gupta [42] | 2018 | Mozambique | CSS | 2015 | 2002 | 13 | NR | 2.3% (8/351) | 3.1% (11/351) |
| Hemming-Schroeder [20] | 2018 | Kenya | CSS | 2003–2015 | 1999 | 4 | Yes | 54.5% (335/615) | 24.2% (142/586) |
| Akala [46] | 2014 | Kenya | CSS | 2008–2012 | 1999 | 9 | NR | 42.2% (326/772) | 20.5% (165/804) |
| Jovel [34] | 2014 | Guinea-Bissau | CT | 2001–2002 | 2008 | 7 | Yes | 36.1% (600/1662) | 36.7% (606/1650) |
| Kateera [40] | 2016 | Rwanda | CSS | 2015 | 2001 | 14 | No | 39.2% (152/388) | 3.7% (14/382) |
| Asare [26] | 2014 | Ghana | CSS | 2012 | 2004 | 8 | Yes | 72% (154/214) | NR |
| Lekana-Douki [39] | 2011 | Gabon | CSS | 2004/2009 | 2005 | 4 | No | 95.2% (219/230) | 66.5% (153/230) |
| Lucchi [22] | 2015 | Kenya | CSS | 2010–2013 | 1999 | 11 | Yes | 9.9% (20/203) | 3.5% (7/200) |
| Ly [30] | 2012 | Senegal | CSS | 2000–2009 | 2003 | BF/AF | Yes | 59.2% (316/532) | 59.2% (316/532) |
| Afsharpad [44] | 2012 | Iran | CSS | 2008–2010 | 2007 | 1 | NR | 94.7% (161/170) | 42.9% (73/170) |
| Mbogo [24] | 2014 | Uganda | CT | 2003–2012 | 2004 | 1 | Yes | 94.3% (807/856) | 34.6% (267/771) |
| Mungthin [33] | 2014 | S. Thailand | CSS | 2009 | 1995 | 14 | Yes | 100% (558/558) | 89.2% (498/558) |
| Mittra [43] | 2006 | India | CSS | 2000–2004 | 1982 | 26 | NR | 84.2% (223/265) | 30.1% (72/239) |
| Mwai [21] | 2009 | Kenya | CSS | 1993–2006 | 1999 | NA | Yes | 63% (203/322) | 74.6% (126/169) |
| Mwanza [38] | 2016 | Zambia | CSS | 2010–2013 | 2003 | 7 | No | 0 | NR |
| Ndam [32] | 2017 | Cameroon | CT | 2003–2012 | 2002 | 1 | Yes | 42.9% (111/259) | NR |
| Ndiaye [31] | 2012 | Senegal | CSS | 2009–2011 | 2003 | 6 | Yes | 18.7% (84/449) | NR |
| Ogouyemi-Hounto [23] | 2013 | Benin | CSS | 2011 | 2004 | 7 | Yes | 93.9% (200/213) | 57.1% (121/212) |
| Okombo [18] | 2014 | Kenya | CSS | 1995–2013 | 2004 | 9 | Yes | 57.9% (212/366) | 51.6% (119/231) |
| Afoakwah [27] | 2014 | Ghana | CSS | 2010–2011 | 2004 | 6 | Yes | 58.5% (144/246) | NR |
| Otienoburu [47] | 2016 | Liberia | CT | 2008–2009 | 2003 | 5 | NR | 93.5% (275/294) | 69.4% (204/294) |
| Some [78] | 2016 | Burkina Faso | CT | 2012 | 2005 | 7 | NR | 24.6% (58/236) | 19.3% (46/238) |
| Sondo [79] | 2015 | Burkina Faso | CT | 2010–2012 | 2005 | 5 | NR | 20.5% (120/584) | NR |
| Thomsen [16] | 2013 | Mozambique | CSS | 2009–2010 | 2002 | 7 | Yes | 43.1% (163/378) | 35.4% (134/378) |
| Raman [17] | 2011 | Mozambique | CSS | 2006–2010 | 2002 | 4 | Yes | 76.9% (1694/2203) | 0 |
| Duah [25] | 2013 | Ghana | CSS | 2003–2010 | 2005 | BF/AF | Yes | 52.1% (554/1063) | 47.8% (372/778) |
| Mohammed [80] | 2013 | Tanzania | CSS | 2010–2011 | 2001 | 9 | NR | 5.7% (42/741) | NR |
CSS cross-sectional, BF/AF before/after, NR not reported, CQ chloroquine, PC policy change