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. 2019 Mar 15;17:63. doi: 10.1186/s12916-019-1295-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Association of the rate of change in Mini-Mental State Examination (MMSE) score with mortality (hazard ratios are indicated by solid lines and 95% confidence intervals by shaded areas, reference point is the lowest value of rate of change in MMSE score, with knots placed at 5th, 35th, 65th and 95th percentiles), after adjusting for baseline cognitive function, age, sex, cohort, education, occupation, type of residence, marital status, co-residence, smoking, alcohol intake, exercise, hypertension, diabetes, heart disease, cerebrovascular disease, respiratory disease, body mass index and psychological distress