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. Author manuscript; available in PMC: 2019 Mar 15.
Published in final edited form as: Diabetes Obes Metab. 2010 Nov;12(11):994–1003. doi: 10.1111/j.1463-1326.2010.01290.x

Table 2.

Demographic characteristics of 10 islet transplant recipients (5 islet transplant alone and 5 islet after kidney transplants).

Subject no. Islet alone (ITA) or islet after kidney (IAK) Immunosuppressive regimen Number of infusions Total number of IEQ Total IEQ/kg Obtained insulin independence? Insulin independent at 1 year post-final transplant? Number of days insulin independent Units of insulin required
(12 months post-initial transplant)
Units of Insulin required
(12 months post-final transplant)
Number of severe hypoglycaemic episodes at 1 year post-initial transplant HgbA1c
Pretransplant 1 year post-initial transplant 3 months post-final transplant 6 months post-final transplant 9 months post-final transplant 12 months post-final transplant
i ITA Dac, Tac., Sir. 3 1 269 000 20 466 Y Y 1790 13 0 0 5.9 5.3 5.3 6.7 7.4 ND
2* ITA Dac, Tac., MMF 2 834 000 11 440 N N 0 24 * * 8.9 * 7.9 * * *
3 IAK Dac, Tac., Sir MMF 3 1 178 659 17 886 Y Y 372 0 0 0 7.5 4.5 <4 4.4 4.6 4.8
4 ITA Dac, Tac., Sir 3 2 548 932 31 810 N N 0 32 25 0 7.4 6.7 5.8 6.8 6.9 6.9
5** ITA Dac, Tac., Sir 2 2 020 000 27 419 Y N 270 0 20 0 8 5.6 5.8 5.6 6.5 6.3
6 ITA Dac, Tac., Sir MMF 2 1 782 111 25 817 Y Y 1596 0 0 0 7.3 5.6 5.2 5.6 5.1 5.6
7 ITA Dac, Tac., Sir 3 2 032 850 29 614 Y N 63 10 15 0 7.1 7.4 7.0 7.4 8 8.4
8 IAK Dac, Tac., Sir Myfortic 2 1 334 700 25 430 Y Y 1465 0 0 0 7.7 5.3 6 6.1 5.3 5.3
9 IAK Dac, Tac., Sir MMF 2 1 061 310 19 187 Y Y 631 0 0 0 6.7 5.9 5.8 6.0 NA 5.9
10 IAK Dac, Tac., Sir Dac, Tac., Sir M 2 994 350 18 397 Y Y 521 0 0 0 7.5 5.8 6.1 5.7 5.8 5.6

Patients received an average of 22 746 ± 6289 IEQ/kg body weight. Eight patients achieved insulin independence. Six of 10 patients remained insulin independent > 1 year. Six patients required two infusions and the remaining four patients received three infusions.

*

Subject no. 2 withdrew from the study.

**

Patient is waiting for third transplant.

As of 2 May 2010.