Table 4.
Plasma FFA dynamics during the FSIVGTT.
| Pre-Tx | 12 months post-Tx | NDC | p (pre-Tx to NDC) | p (pre- vs. post-Tx) | |
|---|---|---|---|---|---|
| Baseline (μmol/l) | 424 ± 104 | 245 ± 48 | 391 ± 64 | 0.85 | 0.13 |
| Nadir (μmol/l) | 131 ± 37 | 62 ± 14 | 102 ± 40 | 0.66 | 0.08 |
| AUC insulin phase 1 (pmol/l-min) | 25 ± 61 | 637 ± 251 | 1418 ± 235 | 0.0001 | 0.06 |
| Mean FFA phase 1 (μmol/l) | 505 ± 125 | 333 ± 48 | 410 ± 104 | 0.66 | 0.20 |
| Mean FFA 0–20 min (μmol/l) | 500 ± 120 | 303 ± 42 | 364 ± 98 | 0.51 | 0.13 |
| Fractional disposal rate (%)/min(10–40) | −2.5 ± 0.9 | −3.2 ± 1.6 | −1.8 ± 2.3 | 0.73 | 0.70 |
| Fractional disposal rate (%)/min(10–20) | −0.9 ± 0.7 | −5.3 ± 2.7 | −6.9 ± 1.6 | 0.0007 | 0.06 |
| Fractional disposal rate (%)/min(20–40) | −5.2 ± 1.8 | −3.9 ± 2.3 | 0.1 ± 2.0 | 0.12 | 0.67 |
| AUC insulin phase 2 (pmol/l·min) | 22 530 ± 5442 | 11 056 ± 1808 | 13 162 ± 3742 | 0.32 | 0.05 |
| Fractional disposal rate (%)/min(10–70) | −1.9 ± 0.4 | −1.4 ± 0.2 | −1.0 ± 0.5 | 0.26 | .033 |
| Mean FFA phase 3 (μmol/l·min) | 348 ± 43 | 288 ± 34 | 335 ± 13 | 0.85 | 0.29 |
AUC, area under the curve; FFA, free fatty acid; Tx, transplant.