Table IV.
The effect of infusion with rHDL or placebo on plasma inflammatory mediators
| Inflammatory mediator | Group | Baseline | 24 hr | 48 hr |
|---|---|---|---|---|
| IL-6 (pg/mL) | rHDL | 54.65 ± 16.05 | 47.21 ± 10.29 | 58.57 ± 37.62 |
| Placebo | 57.95 ± 24.76 | 55.54 ± 27.68 | 89.48 ± 68.36* | |
| CRP (mg/mL) | rHDL | 8.69 ± 10.1 | 7.51 ± 6.20 | 33.60 ± 33.02† |
| Placebo | 3.31 ± 4.34 | 3.37 ± 3.74 | 45.06 ± 41.39† | |
| MCP-1 (pg/mL) | rHDL | 225.3 ± 218.9 | 157.3 ± 190.3* | 189.7 ± 183.3 |
| Placebo | 144.4 ± 116.6 | 112.2 ± 108.4 | 177.1 ± 146.7 | |
| sCD40 (pg/mL) | rHDL | 292.6 ± 191.1 | 166.5 ± 45.95* | 187.8 ± 137.9 |
| Placebo | 194.4 ± 54.01 | 186.2 ± 53.13 | 181.1 ± 54.63 |
*P < 0.05.
†P < 0.001 (change in plasma concentration from baseline).
Values are presented as mean ± SD.