Fig. 1.

Effects of RARβ agonists 10 on neurite outgrowth. Cerebellar neurons grown on a monolayer of CHO-MAG cells were treated for 24 hr with either vehicle (V) or increasing doses of RARβ agonists (1 × 10⁻⁸–1 × 10⁻⁶ M). Both RARβ agonists increase neurite outgrowth in a dose dependant manner. Results are means from 3 independent experiments. Statistical analysis was done using Student’s t-test between vehicle and each drug’s highest dose. Error bars are SEM and **p ≤ 0.001, *p ≤ 0.01.