. 2019 Apr 15;29(8):995–1000. doi: 10.1016/j.bmcl.2019.02.011

Table 4.

Selective RARβ agonists. Inline graphic

Compd	β EC₅₀ nM^a	α EC₅₀ nM^a	γ EC₅₀ nM^a	Fold selectivity for β over α^a	Fold selectivity for β over γγ^b	cLogP^d
10	1.9	26	11	13	5.6	5.3
AC 261066	12	70	33	5.8	2.8	4.9
CD 2019	0.83	9.2	1.6	11	1.9	8.0

^a,b,d