Table 2.
Effect of IBD on HRQoL, impairment to work and non-work activities, and HRU – bivariate analysis
| Parameters | Outcomes stratified – unadjusted | Outcomes stratified – adjusted | ||||
|---|---|---|---|---|---|---|
| IBD n=441 | Control n=82,944 | P-value | IBD n=441 | Control n=428 | P-value | |
| MCS (mean ± SD/SE) | 44.7±11.6 | 47.8±9.7 | <0.001 | 44.7±0.6 | 47.4±0.1 | <0.001 |
| PCS (mean ± SD/SE) | 49.5±7.3 | 53.4±6.2 | <0.001 | 49.5±0.4 | 52.5±0.1 | <0.001 |
| Health state utility score (mean ± SD/SE) | 0.71±0.14 | 0.76±0.12 | <0.001 | 0.71±0.01 | 0.75±0.002 | <0.001 |
| Absenteeism (mean ± SD/SE [count])a | 9.3±22.1 (271) | 3.0±12.8 (46,781) | <0.001 | 9.3±1.3 (271) | 3.6±0.2 (260) | <0.001 |
| Presenteeism (mean ± SD/SE [count])a | 29.6±28.7 (273) | 20.1±24.2 (47,896) | <0.001 | 29.6±1.7 (273) | 21.5±0.5 (266) | <0.001 |
| Overall work impairment (mean ± SD/SE [count])a | 33.4±32.0 (271) | 21.7±26.1 (46,781) | <0.001 | 33.4±1.9 (271) | 23.3±0.6 (260) | <0.001 |
| Activity impairment (mean ± SD/SE) | 30.0±28.8 | 22.0±25.3 | <0.001 | 30.0±1.4 | 23.6±0.3 | <0.001 |
| Health care provider visits in the past 6 months (mean ± SD/SE) | 11.8±25.9 | 4.5±7.9 | <0.001 | 11.8±1.2 | 5.7±0.2 | <0.001 |
| Hospitalizations in the past 6 months (mean ± SD/SE) | 2.9±10.9 | 0.5±4.3 | <0.001 | 2.9±0.5 | 0.8±0.1 | <0.001 |
| ER visits in the past 6 months (mean ± SD/SE) | 0.9±5.3 | 0.1±1.0 | <0.001 | 0.9±0.3 | 0.2±0.1 | <0.001 |
Notes:
a
Number of patients. SDs and SEs are provided for the unweighted and weighted comparisons, respectively.
Abbreviations: ER, emergency room; HRQoL, health-related quality of life; HRU, health care resource utilization; IBD, inflammatory bowel disease; MCS, mental component summary; PCS, physical component summary; SE, standard error.