Table 1.
Demographic and clinical data for patients with squamous cell carcinoma undergoing radiation therapy (Subset-A, n = 28 or 20).
| Criteria | T0 to T6a | T0 to T18b | ||||
|---|---|---|---|---|---|---|
| Total Pts (M/F) | 28 (23/5) | 20 (16/4) | ||||
| Age | ||||||
| Median | 56 | 56 | ||||
| Mean (SD) | 56.2 (10.8) | 56.3 (7.0) | ||||
| Range | 24–84 | 40–70 | ||||
| Ethnicityc | ||||||
| M C/B/H | 20/2/1 | 15/1/0 | ||||
|
F C/B/H |
4/1/0 |
3/1/0 |
||||
| |
DMFS[+]d |
DMFS[-] |
p-value |
DMFS[+] |
DMFS[-] |
p-value |
| Total Pts (M/F) | 11 (10/1) | 17 (13/4) | 0.330* | 7 (6/1) | 13 (10/3) | 0.639* |
| Radiation Dose (cGy) | ||||||
| Median | 7000 | 7000 | 0.746** | 7000 | 6800 | 0.434** |
| Mean (SD) | 6799 (419) | 6721 (469) | 6839 (286) | 6500 (757) | ||
| Range | 6000–7200 | 5400–7020 | 6000–7020 | 5400–7000 | ||
| DMFS (score) -T0/TX | ||||||
| Median | 35/38 | 35/33 | 35/35.5 | 42/41 | ||
| Mean | 39.2/42.9 | 39.1/38.5 | 35.8/37.6 | 51.5/50.3 | ||
| SSFR (ml/min) -T0/TX | ||||||
| Median | 0.97/0.23 | 0.99/0.29 | 0.452/0.370** | 0.93/0.38 | 0.63/0.36 | 0.793/0.539** |
| Mean | 1.41/0.21 | 1.16/0.35 | 1.16/0.49 | 1.00/0.36 | ||
aT0 to T6 corresponds to baseline to 6-months post-RT sampling. bT0 to T18 corresponds to baseline to 18-months sampling. cEthnicity: C (Caucasian), B (Black), H (Hispanic) and associated gender: Male (M), Female (F). DMFS is Decayed/Missing/Filled Surfaces scoring. dDMFS [+]: Patients whose DMFS score increased from T0 to T6 or T0 to T18. DMFS [-]: Patients whose DMFS score did not increase from T0 to T6 or T0 to T18. SSFR: stimulated salivary flow rate. SD is standard deviation.
*Chi-squared test
**Mann-Whitney U-test