Table 2.
Multivariate Adjusted Hazard Ratios for Vascular Events and All-Cause Death Among Women with Migraine Headache Compared with Those Without Migraine Headache
| Event | Raw Number of Events |
Adjusted* HR (95% CI) |
|
|---|---|---|---|
| No MH (n = 693) |
MH (n = 224) |
n = 917 | |
| CV event | 120 | 41 | 1.83 (1.22-2.75) |
| CV death or MI | 52 | 16 | 1.64 (0.91-2.95) |
| All-cause death or MI | 131 | 30 | 1.25 (0.74-2.11) |
| CV death | 89 | 21 | 1.23 (0.71-2.13) |
| All-cause death | 142 | 32 | 1.11 (0.72-1.71) |
| n = 888 | |||
| Stroke | 28 | 14 | 2.33 (1.16-4.68) |
| HF | 47 | 14 | 1.30 (0.64-2.63) |
| Angina hospitalization | 178 | 68 | 1.21 (0.89-1.64) |
| MI | 23 | 7 | 1.10 (0.40-3.02) |
CI = confidence interval; CV event = CV death, MI, CHF, or stroke; HF = heart failure; HR = hazard ratio; MH = migraine headache; MI = myocardial infarction.
*
Full model includes: age, race, BMI, history of diabetes, hypertension, dyslipidemia, smoking, family history of coronary artery disease (CAD), (log) WISE CAD severity score and aspirin use.