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. 2019 Mar 15;11:51. doi: 10.1186/s13148-019-0642-0

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Study enrollment and flow diagram. The number of enrolled subjects according to diagnosis and the number of stool samples analyzed in this study. a Samples had insufficient DNA, b Samples either had insufficient human genomic DNA (low COL2A1) or unknown clinical stage