Table 2.
Subtypes of skin stem cells
| Cell type (Refs) | Localization | Specific markers |
|---|---|---|
| Epidermal stem cells [63, 64, 85, 86] | Basal layer of the epidermis | b1high/melanoma chondroitin sulfate proteoglycan positive, α6high/CD71dim, p63 |
| Melanocyte stem cells [87–89] | Follicle bulge region and hair germ | Dct, Pax3, Sox |
| Follicular stem cells [90–93] | Follicle bulge region | CD34, CD200, K15, K19, Lgr5, Lhx2, NFATC1, NFIB, PHLDA1, Sox9 |
| Hematopoietic stem cells [94] | Follicle dermal papillae | CD34 for lymphoid and hematopoietic progenitor cells |
| Sebaceous gland stem cells [95] | Sebaceous glands and infundibulum | Blimp1 |
| Mesenchymal stem-like cells[96] | Dermis | CD70+, CD90+, CD105+, CD34- |
| Neural progenitor cells [97] | Follicle dermal papillae | S100 for schwannomas, peripheral neural tissue astrocytes; HMB45, a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate |
Refs references