Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 15;17:84. doi: 10.1186/s12967-019-1809-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — Necrostatin-1s (NST-1s) inhibits development of rheumatoid arthritis (RA) in the collagen-induced arthritis (CIA) mouse model. a Reduction in arthritis score and arthritis incidence in CIA mice treated with NST-1s. CIA mice were injected intraperitoneally (i.p.) with NST-1s (300 µg/kg) once daily for 14 weeks after CIA induction. b Representative results of the effects of NST-1s on RA development in CIA mice. Tissue specimens obtained from the hind paw joints of each group of mice at the end point of the experiment were analyzed by staining with hematoxylin and eosin (H&E) and Safranin O. *p < 0.05; **p < 0.01; ***p < 0.001