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. 2019 Mar 15;11:50. doi: 10.1186/s13148-019-0643-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Relationship between DLK1-MEG3 CpG site methylation and imprinted gene expression in AML MNCs. a Mann-Whitney analysis of DLK1 and MEG3 expression in AML MNCs based on the methylation values for particular CpG site amplicons. *p < 0.05. b Kruskal-Wallis test of DLK1 and MEG3 expression in AML MNCs based on the pooled CG6–CG9 or CG7 and CG9 amplicon median methylation results. Groups represent the number of CpG site amplicons out of 4 (CG6–9) or 2 (CG7 and CG9) analyzed which exhibited increased methylation relative to their respective median values