Table 3.
Susceptibility of Selected Antimicrobial Agents Against 13 752 Acinetobacter calcoacetius–A. baumannii Complex Isolates Over 4-Year Intervals According to the Geographic Region (SENTRY Program, 1997–2016)
| % Susceptible by Time Perioda (No. of Isolates Tested) | ||||||
|---|---|---|---|---|---|---|
| Acb Complex | 1997–2000 | 2001–2004 | 2005–2008 | 2009–2012 | 2013–2016 | Overall |
| Asia-Pacific | (314) | (346) | (535) | (674) | (458) | (2327) |
| Amikacin | 75.5 | 63.9 | 40.4 | 22.3 | 29.5 | 41.2 |
| Gentamicin | 64.0 | 51.6 | 32.5 | 18.2 | 26.9 | 34.4 |
| Tobramycin | 76.4 | 62.7 | 41.9 | 24.4 | 30.6 | 42.3 |
| Levofloxacin | 64.6 | 54.6 | 31.8 | 15.7 | 19.0 | 32.5 |
| Ampicillin-sulbactam | NT | 59.8 | 35.7 | 17.8 | 20.5 | 26.9 |
| Ceftazidime | 59.6 | 60.1 | 31.8 | 17.1 | 20.7 | 33.3 |
| Imipenem | 89.2 | 70.8 | 43.0 | 18.4 | 21.6 | 42.0 |
| Meropenem | 88.9 | 71.4 | 43.0 | 18.5 | 21.0 | 42.0 |
| Minocycline | NT | 100.0 | 84.9 | 79.8 | 74.2 | 80.3 |
| Colistin | NT | NT | 99.1 | 99.0 | 93.7 | 97.5 |
| Europe | (540) | (536) | (705) | (1125) | (1625) | (4531) |
| Amikacin | 31.7 | 40.7 | 32.9 | 32.4 | 22.7 | 29.9 |
| Gentamicin | 20.8 | 31.5 | 27.5 | 27.3 | 24.9 | 26.2 |
| Tobramycin | 48.3 | 47.4 | 50.6 | 46.4 | 42.4 | 46.0 |
| Levofloxacin | 24.4 | 26.5 | 20.9 | 15.8 | 13.7 | 18.1 |
| Ampicillin-sulbactam | NT | 40.5 | 31.5 | 25.9 | 19.2 | 25.2 |
| Ceftazidime | 25.0 | 29.5 | 23.4 | 17.3 | 15.1 | 19.8 |
| Imipenem | 64.6 | 61.6 | 50.6 | 42.4 | 23.7 | 39.4 |
| Meropenem | 55.7 | 55.7 | 47.7 | 28.2 | 22.2 | 35.6 |
| Minocycline | NT | 89.9 | 82.5 | 71.5 | 64.2 | 70.1 |
| Colistin | NT | NT | 99.2 | 97.7 | 89.6 | 93.9 |
| Latin America | (507) | (414) | (910) | (1126) | (410) | (3367) |
| Amikacin | 22.7 | 27.8 | 22.3 | 23.0 | 17.6 | 22.7 |
| Gentamicin | 27.0 | 28.0 | 30.9 | 28.2 | 22.0 | 28.0 |
| Tobramycin | 39.8 | 43.2 | 45.3 | 45.0 | 49.3 | 44.6 |
| Levofloxacin | 23.1 | 22.9 | 15.3 | 7.8 | 12.4 | 14.6 |
| Ampicillin-sulbactam | NT | 43.7 | 29.3 | 13.4 | 16.4 | 21.6 |
| Ceftazidime | 22.7 | 21.5 | 15.3 | 8.5 | 13.4 | 14.7 |
| Imipenem | 87.8 | 80.7 | 49.1 | 19.4 | 14.4 | 44.7 |
| Meropenem | 81.3 | 70.6 | 45.4 | 18.4 | 13.7 | 41.0 |
| Minocycline | NT | 100.0 | 94.2 | 90.9 | 83.9 | 91.1 |
| Colistin | NT | NT | 99.2 | 98.0 | 96.6 | 98.1 |
| North America | (472) | (479) | (548) | (823) | (1205) | (3527) |
| Amikacin | 83.7 | 74.1 | 62.2 | 54.4 | 69.9 | 67.5 |
| Gentamicin | 67.8 | 53.0 | 46.2 | 44.1 | 59.2 | 54.0 |
| Tobramycin | 80.3 | 72.0 | 60.2 | 52.4 | 69.6 | 65.9 |
| Levofloxacin | 64.4 | 45.3 | 36.7 | 37.7 | 49.1 | 46.0 |
| Ampicillin-sulbactam | NT | 65.8 | 54.6 | 45.6 | 58.9 | 54.7 |
| Ceftazidime | 67.6 | 48.4 | 38.3 | 39.6 | 51.5 | 48.4 |
| Imipenem | 92.6 | 81.8 | 62.8 | 46.8 | 57.7 | 63.9 |
| Meropenem | 88.8 | 71.8 | 58.6 | 43.7 | 54.9 | 59.7 |
| Minocycline | NT | 90.0 | 78.3 | 74.3 | 84.9 | 81.6 |
| Colistin | NT | NT | 98.4 | 96.6 | 93.6 | 95.4 |