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. 2019 Mar 15;2019(3):CD011671. doi: 10.1002/14651858.CD011671.pub2
Methods
  • Study design: parallel RCT

  • Duration of study: not reported

  • Duration of follow‐up: 1 year

Participants
  • Country: Minnesota, USA

  • Setting: single centre

  • Donor characteristics

    • Mean age ± SD (years): not reported

    • Number of DCD: not reported

    • Number of ECD: not reported

    • Sex (M/F); not reported

    • Inclusion criteria: not reported

    • Exclusion criteria: not reported

  • Recipient characteristics

    • Inclusion criteria: not reported

    • Exclusion criteria: not reported

    • Sex (M/F): not reported

    • Mean age ± SD (years): not reported

Interventions Machine perfusion
  • Waters Mox‐100 pulsatile perfusion machine using silica gel fractionated plasma


Static cold storage
  • Euro‐Collins solution


Mean CIT
  • Data on length of CIT was not reported, but there was a randomisation procedure as to which organ was transplanted first

Outcomes
  • DGF

  • One year graft survival

Notes
  • 54 kidneys from 27 donors

  • One kidney from each pair assigned to MP and the other to SCS

  • Very short manuscript, lacking a lot of information

  • Funding source: not reported

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement
Allocation concealment (selection bias) Low risk Sealed envelopes were used to decide which kidney would receive MP
Blinding of participants and personnel (performance bias) All outcomes Unclear risk No information on blinding, or on differences in CIT between groups
Blinding of outcome assessment (detection bias) All outcomes Low risk No information, but outcome measurements are unlikely to be affected by the lack of blinding
Incomplete outcome data (attrition bias) All outcomes Unclear risk Insufficient information to permit judgement
Selective reporting (reporting bias) Low risk Appropriate outcomes, adequately reported
Other bias Unclear risk Extremely short manuscript making thorough analysis of biases impossible