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. 2019 Mar 15;2019(3):CD011671. doi: 10.1002/14651858.CD011671.pub2
Methods Multicentre RCT; sequential study design ‐ maximum of 270 recipients
Participants Inclusion criteria
  • Patients who receive a kidney transplant from a controlled or uncontrolled cardiac‐death deceased donor

  • Recipient > 18 years


Exclusion criteria
  • Lack of informed consent

  • Positive crossmatch

  • Previous recipient of non‐kidney solid‐organ transplant

Interventions One kidney will be placed upon the LifePort pulsatile perfusion machine. The other will be placed in standard cold‐storage ice‐box.
Outcomes
  • DGF

  • Duration of DGF

  • The area under the curve of the daily SCr level at days 1 to 14

  • Day 14 calculated eGFR

  • The need for dialysis in the first 7 days excluding the first 24 hours post‐transplant

  • Median times to last dialysis

  • Non‐graft function rates, defined as a kidney transplant that fails to provide one month of dialysis free renal replacement, where loss is not attributable directly to rejection or vascular thrombosis

  • Incidence of acute rejection

  • Three and 12‐month graft survival

  • Three and 12‐month SCr

  • Three and 12‐month glomerular filtration rate (MDRD method)

  • Incidence of graft loss for technical reasons, e.g. renal artery or vein thrombosis

  • One‐year patient survival

  • Length of hospital stay

Notes The following is listed as an editorial note in the ISRCTN registry (http://www.isrctn.com/ISRCTN50082383): 18/12/2017: The overall study end date was updated from 01/12/2016 to 31/05/2017.