Methods |
Multicentre RCT; sequential study design ‐ maximum of 270 recipients |
Participants |
Inclusion criteria
Exclusion criteria
|
Interventions |
One kidney will be placed upon the LifePort pulsatile perfusion machine. The other will be placed in standard cold‐storage ice‐box. |
Outcomes |
DGF
Duration of DGF
The area under the curve of the daily SCr level at days 1 to 14
Day 14 calculated eGFR
The need for dialysis in the first 7 days excluding the first 24 hours post‐transplant
Median times to last dialysis
Non‐graft function rates, defined as a kidney transplant that fails to provide one month of dialysis free renal replacement, where loss is not attributable directly to rejection or vascular thrombosis
Incidence of acute rejection
Three and 12‐month graft survival
Three and 12‐month SCr
Three and 12‐month glomerular filtration rate (MDRD method)
Incidence of graft loss for technical reasons, e.g. renal artery or vein thrombosis
One‐year patient survival
Length of hospital stay
|
Notes |
The following is listed as an editorial note in the ISRCTN registry (http://www.isrctn.com/ISRCTN50082383): 18/12/2017: The overall study end date was updated from 01/12/2016 to 31/05/2017. |