NCT02525510

Trial name or title	A randomized trial of mild hypothermia and machine perfusion in deceased organ donors for protection against delayed graft function in kidney transplant recipients
Methods	Parallel assignment RCT to assess the effect of mild hypothermia in the deceased organ donor before organs are recovered, with or without subsequent hypothermic MP of the kidney after recovery and prior to transplantation
Participants	DBD donors > 18 years in the USA
Interventions	Enrolled donors will be divided into two populations based on local organ procurement organization criteria: pump eligible and not pump eligible. These categories will then be split to result in five arms: Pump eligible: normothermia; pump both kidneys Pump eligible: hypothermia; pump right kidney Pump eligible: hypothermia; pump left kidney Not pump eligible: normothermia Not pump eligible: hypothermia
Outcomes	DGF Graft and patient survival at 1 year
Starting date	26/07/2017
Contact information	Claus Niemann, MD; Claus.Niemann@ucsf.edu Darren Malinoski, MD; malinosk@ohsu.edu
Notes	Estimated completion date 26/07/2021