Fig. 1. Upper panel: mapping onto the Ub structure of the intensity variations of the ¹H and ¹⁵N amide cross-peaks after the addition of Aβ40 defines a neat region of the peptide interaction. The residues whose peaks were reduced in intensity are represented in red. Lower panel: ¹H and ¹⁵N amide cross-peaks intensity variations of the Ub HSQC spectrum after the addition of 30 μM Aβ40 reported as a function of protein residue numbers.